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Figure 2: Nodular lung lesion histology by percutaneous lung biopsy. (a) The alveolar fibrous thickness and various lymphocyte infiltrations were found, suggesting pembrolizumab-induced pneumonitis accompanied with OP (H and E, ×100). (b) CD3+ cell immunohistochemical analysis in inflammatory lesions (×400). (c) CD4+ cell staining (×200). (d) CD8+ cell staining (×200). (e) PD-L1 in inflammatory lesion staining (×200). (f) PD-L2 in inflammatory lesion staining (×200). OP: Organizing pneumonia

Figure 2: Nodular lung lesion histology by percutaneous lung biopsy. (a) The alveolar fibrous thickness and various lymphocyte infiltrations were found, suggesting pembrolizumab-induced pneumonitis accompanied with OP (H and E, ×100). (b) CD3+ cell immunohistochemical analysis in inflammatory lesions (×400). (c) CD4+ cell staining (×200). (d) CD8+ cell staining (×200). (e) PD-L1 in inflammatory lesion staining (×200). (f) PD-L2 in inflammatory lesion staining (×200). OP: Organizing pneumonia