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Figure 1: SKA1 upregulation in ESCC tissues is significant. (a) Immunohistochemistry staining of SKA1 expression in ESCC tissues (n = 113) (×400). (b) Immunohistochemistry staining of SKA1 expression in CHEM tissues (n = 113) (×400). (c) Levels of SKA1 mRNA expression in ESCC tissues (n = 40) and CHEM tissues (n = 40) measured by reverse transcription–quantitative polymerase chain reaction. (d) Increased SKA1 mRNA expression in ESCC tissues compared to healthy tissues in The Cancer Genome Atlas, performed using the online tool UALCAN. **P < 0.01; ***P < 0.001. ESCC: Esophageal squamous cell carcinoma; CHEM: Corresponding healthy esophageal mucosa; SKA1: Spindle- and kinetochore-associated protein 1

Figure 1: SKA1 upregulation in ESCC tissues is significant. (a) Immunohistochemistry staining of SKA1 expression in ESCC tissues (<i>n</i> = 113) (×400). (b) Immunohistochemistry staining of SKA1 expression in CHEM tissues (<i>n</i> = 113) (×400). (c) Levels of SKA1 mRNA expression in ESCC tissues (<i>n</i> = 40) and CHEM tissues (<i>n</i> = 40) measured by reverse transcription–quantitative polymerase chain reaction. (d) Increased SKA1 mRNA expression in ESCC tissues compared to healthy tissues in The Cancer Genome Atlas, performed using the online tool UALCAN. **<i>P</i> < 0.01; ***<i>P</i> < 0.001. ESCC: Esophageal squamous cell carcinoma; CHEM: Corresponding healthy esophageal mucosa; SKA1: Spindle- and kinetochore-associated protein 1