Figure 2: CT scan after 16 months of Apatinib treatment. (2A and 2B) the previous large, heterogeneously enhancing mass lesion with small pieces of bone density in the thoracic cavity was greatly reduced to 10cm*10cm*11cm in size. Most of them were necrotic areas in the mass. No pleural effusion was found around the mass. (Fig. 2C) another large, heterogeneously enhancing mass lesion in left sacrum-ilium region was not changed much. (Fig. 2D) an angiogram showed not as rich blood supply as before in the lesion and failed again to detect the main tumor-feeding arteries into the mass. 2D 1-5 showed arteries surrounded the lesion without entering the lesion.