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Figure 5: Pyruvate kinase M2 expression connected with MMP2 and MMP9 expression. Pyruvate kinase M2 expression influence the p38 level. (a and b) MMP2, MMP9, and p38 expression were measured of groups of small interfering-pyruvate kinase M2 and small interfering-pyruvate kinase M2+ pyruvate kinase M2. (c and d) MMP2, MMP9, and p38 expression were measured of groups of small interfering-pyruvate kinase M2+ SB203580 and pyruvate kinase M2+ small interfering-pyruvate kinase M2+ SB203580. Each assay was done in triplicate and repeated at least thrice. Error bars indicate means ± standard deviation and *P < 0.05, **P < 0.01 and ***P < 0.001 compared with control group

Figure 5: Pyruvate kinase M2 expression connected with MMP2 and MMP9 expression. Pyruvate kinase M2 expression influence the p38 level. (a and b) MMP2, MMP9, and p38 expression were measured of groups of small interfering-pyruvate kinase M2 and small interfering-pyruvate kinase M2+ pyruvate kinase M2. (c and d) MMP2, MMP9, and p38 expression were measured of groups of small interfering-pyruvate kinase M2+ SB203580 and pyruvate kinase M2+ small interfering-pyruvate kinase M2+ SB203580. Each assay was done in triplicate and repeated at least thrice. Error bars indicate means ± standard deviation and *<i>P</i> < 0.05, **<i>P</i> < 0.01 and ***<i>P</i> < 0.001 compared with control group