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Figure 1: Follicular dendritic cell sarcoma. (a) Gross view of the lobulated fleshy tumor with areas of hemorrhage in submucosal region of the anal canal. (b) Plump spindle cells in focal whorl formations (H and E stain, x200). (c) Immunohistochemical diffuse cytoplasmic positivity for CD21 (x200). (d) Diffuse positivity for CD23 brings out the whorls of the tumor architecture (x200). (e) Focal variable positivity for CD35 (x200). (f) Diffuse cytoplasmic positivity on immunohistochemistry for vimentin (x200). Epithelium on lower left of the frame C and F is negative

Figure 1: Follicular dendritic cell sarcoma. (a) Gross view of the lobulated fleshy tumor with areas of hemorrhage in submucosal region of the anal canal. (b) Plump spindle cells in focal whorl formations (H and
E stain, x200). (c) Immunohistochemical diffuse cytoplasmic positivity for CD21 (x200). (d) Diffuse positivity for CD23 brings out the whorls of the tumor architecture (x200). (e) Focal variable positivity for CD35 (x200). (f) Diffuse cytoplasmic positivity on immunohistochemistry for vimentin (x200). Epithelium on lower left of the frame C and F is negative