Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 16  |  Issue : 6  |  Page : 1265--1268

Diagnostic accuracy of sentinel lymph node biopsy in determining the axillary lymph node metastasis


Ozlem Okur1, Julide Sagiroglu1, Gozde Kir2, Nurgul Bulut3, Orhan Alimoglu1 
1 Department of General Surgery, Goztepe Education and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey
2 Department of Pathology, Goztepe Education and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey
3 Department of Biostatistics and Medical Informatics, Istanbul Medeniyet University, Istanbul, Turkey

Correspondence Address:
Ozlem Okur
Egitim Mahallesi Dr. Erkin Cad. Goztepe Egitim Arastirma Hastanesi, Istanbul
Turkey

Background: Sentinel lymph node biopsy (SLNB) is accepted as the standard procedure to determine the axillary lymph node metastasis in breast cancer at early stage. However, in many cases with sentinel lymph node positivity, the axilla does not contain any tumor cells. As a result, the accuracy of SLNB to predict axillary lymph node metastasis must be evaluated. Patients and Methods: Thousand hundred and fourteen women operated for breast cancer were retrospectively examined. Breast cancer patients without axillary metastasis on clinical examination who had undergone SLNB were included in the study. Sentinel lymph node positivity and axillary lymph node positivity were compared. Results: Among 1114 women operated for breast cancer, 230 were clinically node negative preoperatively and undergone SLNB. Eighty-three (36%) of the patients were SLNB positive and undergone axillary dissection. Forty-three (51.8%) of them had tumor positive axillary lymph nodes and 40 (48.2%) of them had tumor negative axillary lymph nodes. Interpretation: In 48.2% of the patients, positive sentinel lymph node does not demonstrate a positive axilla. This finding supports sparing axillary dissection in patients with favorable prognostic factors even if the sentinel lymph node is found to be positive. Conclusion: Axillary lymph node dissection(ALND) may be spared even if there are macrometastatic sentinel lymph nodes in patients with favorable tumor types who will undergo breast-conserving surgery.


How to cite this article:
Okur O, Sagiroglu J, Kir G, Bulut N, Alimoglu O. Diagnostic accuracy of sentinel lymph node biopsy in determining the axillary lymph node metastasis.J Can Res Ther 2020;16:1265-1268


How to cite this URL:
Okur O, Sagiroglu J, Kir G, Bulut N, Alimoglu O. Diagnostic accuracy of sentinel lymph node biopsy in determining the axillary lymph node metastasis. J Can Res Ther [serial online] 2020 [cited 2022 Jan 24 ];16:1265-1268
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=6;spage=1265;epage=1268;aulast=Okur;type=0