Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 16  |  Issue : 5  |  Page : 1051--1055

Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma


Junbo Zhang, Yuangang Lu, Xingcun Zhang, Yunchuan Yang, Huiling Kou, Yuanyuan Wang 
 Department of Plastic and Cosmetic Surgery, Daping Hospital, Army Military Medical University, Chongqing, China

Correspondence Address:
Yuanyuan Wang
Department of Plastic and Cosmetic Surgery, Daping Hospital, Army Military Medical University, 10 Changjiang Branch Road, Daping, Chongqing 400042
China

Purpose: The purpose of this study is to investigate the clinical efficacy of Mohs surgery in combination with topical photodynamic therapy (PDT) for facial basal cell carcinoma. Patients and Methods: Eighty-six patients with facial basal cell carcinoma treated in our department from April 2011 to December 2013 were included. Mohs surgery was used to remove the lesions followed by direct suturing, skin flap grafting, or medium thickness free-skin grafting to repair the incisions. Topical PDT was performed three times, at an interval of 2 weeks, immediately after the sutures were removed. The patients were followed up for 2 years after the operation to evaluate tumor recurrence. Results: Recurrence was not observed within 1 year after Mohs surgery combining PDT; however, one case of recurrence was found at the 2-year follow-up. Conclusion: The efficacy of Mohs surgery combining topical PDT is a definite treatment for facial basal cell carcinomas, as it reduced the tumor recurrence rate and maintained the relative integrity of the local tissues and appearance. This method could be a new effective treatment method for the facial basal cell carcinoma.


How to cite this article:
Zhang J, Lu Y, Zhang X, Yang Y, Kou H, Wang Y. Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma.J Can Res Ther 2020;16:1051-1055


How to cite this URL:
Zhang J, Lu Y, Zhang X, Yang Y, Kou H, Wang Y. Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma. J Can Res Ther [serial online] 2020 [cited 2020 Nov 30 ];16:1051-1055
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=5;spage=1051;epage=1055;aulast=Zhang;type=0