Effect of Au-197 nanoparticles along with Sm-153 radiopharmaceutical in prostate cancer from simulation method :Akbar Abbasi, Fahreddin Sadikoglu, Mostafa Hassanzadeh, Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year : 2019 | Volume : 15 | Issue : 8 | Page : 42--46

Effect of Au-197 nanoparticles along with Sm-153 radiopharmaceutical in prostate cancer from simulation method

Akbar Abbasi¹, Fahreddin Sadikoglu², Mostafa Hassanzadeh⁴
¹ Faculty of Engineering, University of Kyrenia, Girne, Turkey; Reactor Research School, Nuclear Science and Technology Institute (NSTRI), Tehran, Iran
² Department of Electrical and Electronic Engineering, Near East University, Nicosia, North Cyprus, Mersin 10, Turkey

Correspondence Address:
Dr. Akbar Abbasi
University of Kyrenia, Kyrenia, North Cyprus, Mersin 10

Aims: Based on recent studies, it was indicated that gold (Au-197) nanoparticles could be safely prescribed and used to enhance the absorbed dose during radiation therapy. Subjects and Methods: We evaluated the samarium-153 (Sm-153) radiopharmaceutical and Au-197 and Sm-153 radiopharmaceutical absorbed dose rate by means of the Monte Carlo technique in prostate cancer. Results: The results show that absorbed dose rate in entire prostate volume due to 20 mCi of Sm-153 radiopharmaceutical is 27.339 μGy/s, 48.837 μGy/s, and 76.176 μGy/s for γ-interaction, β¯ particle interaction, and γ+β¯ interaction, respectively. The results in the exterior of the prostate for β¯ interaction, β¯ particle interaction, and γ+β¯ interaction were 20.971 μGy/s, 1.110 μGy/s, and 22.081 μGy/s, respectively. Conclusions: The calculation results for Au-197 and Sm-153 radiopharmaceutical show that the absorbed dose rate in entire prostate volume 3% was increased and undesirable dose value in exterior of prostate 7% was decreased.

How to cite this article:
Abbasi A, Sadikoglu F, Hassanzadeh M. Effect of Au-197 nanoparticles along with Sm-153 radiopharmaceutical in prostate cancer from simulation method.J Can Res Ther 2019;15:42-46

How to cite this URL:
Abbasi A, Sadikoglu F, Hassanzadeh M. Effect of Au-197 nanoparticles along with Sm-153 radiopharmaceutical in prostate cancer from simulation method. J Can Res Ther [serial online] 2019 [cited 2021 Jan 26 ];15:42-46
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2019;volume=15;issue=8;spage=42;epage=46;aulast=Abbasi;type=0