Journal of Cancer Research and Therapeutics

BRIEF COMMUNICATION
Year
: 2019  |  Volume : 15  |  Issue : 3  |  Page : 690--692

Metastasis-associated fibroblasts in oral squamous cell carcinoma: An illusion or a reality


Anjali P Ganjre 
 Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India

Correspondence Address:
Dr. Anjali P Ganjre
Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra
India

Fibroblasts at the pre-metastatic site exhibited characteristic trait for creation of metastatic milieu which aid in the formation of distant metastasis, and are called as metastasis associated fibroblasts (MAFs).Array of studies showed that MAF bears similar attributes as that of carcinoma associated fibroblasts present in primary tumor. MAFs showed expression of specific type of molecules and pathways to form required pre-metastatic microenvironment at the distant site. It will be important to unrevealed characteristics features in OSCC so as to help in implicating the new therapeutic strategies.


How to cite this article:
Ganjre AP. Metastasis-associated fibroblasts in oral squamous cell carcinoma: An illusion or a reality.J Can Res Ther 2019;15:690-692


How to cite this URL:
Ganjre AP. Metastasis-associated fibroblasts in oral squamous cell carcinoma: An illusion or a reality. J Can Res Ther [serial online] 2019 [cited 2020 Oct 24 ];15:690-692
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2019;volume=15;issue=3;spage=690;epage=692;aulast=Ganjre;type=0