Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 14  |  Issue : 1  |  Page : 128--132

Multislice spiral computed tomography in the differential diagnosis of ground-glass opacity


Jianqiang Yu1, Shiqiang Zhu1, Zufeng Ge1, Beilei Shen1, Yazhi Shen1, Chaojun Wang1, Xiong Fang1, Jian Dai2 
1 Department of Radiology, Fenghua District Peoples' Hospital, Ningbo, PR China
2 Department of Radiology, Cixi People's Hospital, Zhejiang Province, PR China

Correspondence Address:
Dr. Jian Dai
Department of Radiology, Cixi People's Hospital, Zhejiang Province 315300
PR China

Objective: This study aimed to evaluate the value of multislice spiral computed tomography (CT) in differential diagnosis of benign or malignant pulmonary ground-glass opacity (GGO). Materials and Methods: A total of 68 patients with pulmonary GGO who received surgical treatment in our hospital from January 2014 to January 2017 were retrospectively analyzed. Postoperative pathology showed that there were 22 cases of benign GGO and 47 cases of malignant GGO (adenocarcinoma). The diameter, maximum CT value, and mean CT value of benign and malignant GGOs were determined and compared. The clinical value of identifying benign or malignant GGOs with these indices was analyzed through receiver operating characteristic (ROC) curve. Results: The mean GGO diameter, maximum CT value, and mean CT value in the benign group were significantly lower than those of in the malignant group, and the difference was statistically significant (P < 0.05). The diameter, maximum CT value, and mean CT value of GGO were applied to identify benign or malignant GGO: sensitivity was 60.87%, 69.57%, and 63.04%; and the specificity was 63.64%, 63.64%, and 81.82%; the cutoff values were 13.89 (mm), 26.18 (Hu), and 24.61 (Hu); and areas under the ROC curves were 0.66, 0.71, and 0.69, respectively. Conclusion: The possibility of malignancy has been significantly increased for GGOs with a large diameter, high mean CT value and maximum CT value. Surgical treatment should be performed for this type of GGOs.


How to cite this article:
Yu J, Zhu S, Ge Z, Shen B, Shen Y, Wang C, Fang X, Dai J. Multislice spiral computed tomography in the differential diagnosis of ground-glass opacity.J Can Res Ther 2018;14:128-132


How to cite this URL:
Yu J, Zhu S, Ge Z, Shen B, Shen Y, Wang C, Fang X, Dai J. Multislice spiral computed tomography in the differential diagnosis of ground-glass opacity. J Can Res Ther [serial online] 2018 [cited 2020 Oct 29 ];14:128-132
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2018;volume=14;issue=1;spage=128;epage=132;aulast=Yu;type=0