Journal of Cancer Research and Therapeutics

CORRESPONDENCE
Year
: 2018  |  Volume : 14  |  Issue : 10  |  Page : 800--802

Trisomy 3 as an acquired cytogenetic abnormality in primary acute megakaryoblastic leukemia


Vahid Fallah Azad1, Azim Mehrvar1, Narjes Mehrvar2 
1 MAHAK Pediatric Cancer Treatment and Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Correspondence Address:
Narjes Mehrvar
Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran
Iran

Acute myeloid leukemia has a rare subtype in French-American-British classification as M7 or acute megakaryoblastic leukemia. Chromosome abnormalities in cases with acute megakaryoblastic leukemia can affect their prognosis. Evaluation of these abnormalities and their impact are not fully elucidated. This case presentation is about 16 months female who has a rare abnormality (trisomy 3) alongside acute megakaryoblastic leukemia. The remarkable point is that her malignancy is as primary or non-Down syndrome acute megakaryoblastic leukemia. The author's suggestion through this case presentation is the necessity of drawing a cytogenetic profile, especially in cases with acute megakaryoblastic leukemia for better treatment strategies.


How to cite this article:
Azad VF, Mehrvar A, Mehrvar N. Trisomy 3 as an acquired cytogenetic abnormality in primary acute megakaryoblastic leukemia.J Can Res Ther 2018;14:800-802


How to cite this URL:
Azad VF, Mehrvar A, Mehrvar N. Trisomy 3 as an acquired cytogenetic abnormality in primary acute megakaryoblastic leukemia. J Can Res Ther [serial online] 2018 [cited 2020 Nov 29 ];14:800-802
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2018;volume=14;issue=10;spage=800;epage=802;aulast=Azad;type=0