Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 10  |  Issue : 1  |  Page : 11--14

Role of concurrent chemoradiation in inoperable carcinoma esophagus: A prospective study


Virendra Bhandari 
 Department of Radiation Oncology, Sri Aurobindo Institute of Medical Sciences, Medical College, Indore, Madhya Pradesh, India

Correspondence Address:
Virendra Bhandari
401, Samyak Towers, 16/3 Old Palasia
India

Introduction: The treatment of choice in cancer esophagus is controversial. Radiation therapy oncology group, Eastern cooperative oncology group and Cochrane studies have shown superiority of concurrent chemoradiation in inoperable carcinoma esophagus. In these studies full dose cisplatin was given every 3 weeks along with radiotherapy and hence had some toxicity. So, we started treating inoperable carcinoma esophagus patients with low dose weekly cisplatin given concurrently with radiotherapy aiming at low toxicity and similar results. Materials and Methods: A total of 31 cases of inoperable cases of carcinoma esophagus were treated with once weekly cisplatin 30 mg/m 2 along with radiotherapy 60 Gy in 30 fractions in 6 weeks on Telecobalt/Linear accelerator. Results : w0 e could achieve lower toxicity with 80%, 35% and 19% with 1, 2, and 3 year«SQ»s survival with a median survival of 18 months. So, we conclude that this regimen is better than 3 weekly chemotherapy regimen as is better tolerated with less toxicity and similar outcome.


How to cite this article:
Bhandari V. Role of concurrent chemoradiation in inoperable carcinoma esophagus: A prospective study.J Can Res Ther 2014;10:11-14


How to cite this URL:
Bhandari V. Role of concurrent chemoradiation in inoperable carcinoma esophagus: A prospective study. J Can Res Ther [serial online] 2014 [cited 2021 Sep 22 ];10:11-14
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2014;volume=10;issue=1;spage=11;epage=14;aulast=Bhandari;type=0