Journal of Cancer Research and Therapeutics

CORRESPONDENCE
Year
: 2013  |  Volume : 9  |  Issue : 2  |  Page : 284--286

Low-grade myofibroblastic sarcoma of the larynx: A rare entity with review of literature


Divya Khosla1, Budhi Singh Yadav1, Ritesh Kumar1, Sushmita Ghoshal1, Kim Vaiphei2, Roshan Verma3, Suresh C Sharma1 
1 Department of Radiotherapy and Oncology, Regional Cancer Centre, Chandigarh, India
2 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Otolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Budhi Singh Yadav
Department of Radiotherapy and Oncology, Regional Cancer Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Sector 12, Chandigarh - 160012
India

Mesenchymal neoplasms of the larynx are rare and make up approximately 0.3% to 1.0% of all malignancies at this location. Low grade myofibroblastic sarcoma (LGMS) of larynx is a rare entity. We describe a rare case of LGMS of larynx who presented with complaint of hoarseness of voice. The patient was treated with total laryngectomy plus partial pharyngectomy followed by post-operative radiotherapy. Histopathologically, the lesion was composed of spindle cells that manifested variable cellular anaplasia and expressed smooth muscle actin (SMA) and focally S-100.One of the resection limits was involved so patient was given post-operative radiotherapy. The patient is alive and disease free 14 months after surgery. The characteristic clinical, histopathological features and treatment of this case are described with a literature review.


How to cite this article:
Khosla D, Yadav BS, Kumar R, Ghoshal S, Vaiphei K, Verma R, Sharma SC. Low-grade myofibroblastic sarcoma of the larynx: A rare entity with review of literature.J Can Res Ther 2013;9:284-286


How to cite this URL:
Khosla D, Yadav BS, Kumar R, Ghoshal S, Vaiphei K, Verma R, Sharma SC. Low-grade myofibroblastic sarcoma of the larynx: A rare entity with review of literature. J Can Res Ther [serial online] 2013 [cited 2022 Oct 5 ];9:284-286
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2013;volume=9;issue=2;spage=284;epage=286;aulast=Khosla;type=0