Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2009  |  Volume : 5  |  Issue : 1  |  Page : 8--13

Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: The Greek experience


Maria-Aggeliki Kalogeridi1, Paraskevi Georgolopoulou2, Vassilis Kouloulias1, John Kouvaris1, George Pissakas3 
1 Radiotherapy Unit, Medical School, National University of Athens, Greece
2 Department of Medical Physics, St Savvas Anticancer Hospital, Athens, Greece
3 Department of Radiotherapy, Alexandras General Hospital, Athens, Greece

Correspondence Address:
Maria-Aggeliki Kalogeridi
12 Karaiskaki, St. GR-15562, Holargos
Greece

Purpose: To estimate the value of LINAC-based stereotactic radiosurgery (SRS) for the long-term local control of unilateral acoustic neuromas. Materials and Methods: Twenty patients (median age 66; range 57-80 years) with unilateral acoustic neuroma underwent LINAC-based SRS from May 2000 through June 2004 with a dose of 11-12 Gy. The follow-up period ranged from 36 to 84 months (median follow-up period: 55 months). Before SRS none of the patients had useful hearing. The follow-up consisted of repeat imaging studies and clinical examination for assessment of facial and trigeminal nerve function at 6-month intervals for the first year and yearly thereafter. Results: Eleven tumors (58%) decreased in size and eight (42%) remained stable. One tumor showed a minor increase in size on the MRI done 6 months after SRS in comparison with the pretreatment MRI; however, a subsequent decrease was noticed on the next radiographic assessment and the tumor remained stable from then on. None of the tumors increased in size in the long-term follow-up, thus giving an overall growth control of 100% for the patients in this study. None of the patients had useful hearing before SRS, so hearing level was not assessed during follow-up. No patient developed new, permanent facial or trigeminal neuropathy. Conclusion: LINAC-based SRS with 11-12 Gy provides excellent tumor control in acoustic neuroma and has low toxicity even after long-term follow-up.


How to cite this article:
Kalogeridi MA, Georgolopoulou P, Kouloulias V, Kouvaris J, Pissakas G. Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: The Greek experience.J Can Res Ther 2009;5:8-13


How to cite this URL:
Kalogeridi MA, Georgolopoulou P, Kouloulias V, Kouvaris J, Pissakas G. Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: The Greek experience. J Can Res Ther [serial online] 2009 [cited 2020 Oct 25 ];5:8-13
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2009;volume=5;issue=1;spage=8;epage=13;aulast=Kalogeridi;type=0