Journal of Cancer Research and Therapeutics

CASE REPORT
Year
: 2007  |  Volume : 3  |  Issue : 2  |  Page : 96--99

Post-irradiation angiosarcoma of bone


Srabani Mittal1, Chanchal Goswami1, Nandini Kanoria2, Aniruddha Bhattacharya1 
1 Department of Medical Oncology, B P Poddar Hospital and Medical Research Ltd., Kolkata, India
2 Department of Pathology, B P Poddar Hospital and Medical Research Ltd., Kolkata, India

Correspondence Address:
Srabani Mittal
71/1, Humayun Kabir Sarani, New Alipore, Block - G, Kolkatta - 700 053
India

Radiation therapy is extensively used for treatment of malignancies, but angiosarcomas occurring in an irradiated area are uncommon. We report a rare case of high-grade epithelioid angiosarcoma of upper end of right humerus in a 67-year-old male occurring ten years following irradiation for giant cell tumor of the same anatomical site. The patient presented with progressive painful swelling over right shoulder and his X-ray showed erosion of medial cortex with lytic areas at upper end of humerus. He underwent excision of affected part of humerus followed by cemented hemiarthroplasty and bone grafting. After initial histopathological diagnostic dilemma the final report was given as post-radiation angiosarcoma. Disease recurred at the end of one-year follow-up period where upon he underwent wide resection with prosthesis replacement. He received four cycles of combination chemotherapy with doxorubicin and ifosfamide and currently is free of recurrence after six months follow -up.


How to cite this article:
Mittal S, Goswami C, Kanoria N, Bhattacharya A. Post-irradiation angiosarcoma of bone.J Can Res Ther 2007;3:96-99


How to cite this URL:
Mittal S, Goswami C, Kanoria N, Bhattacharya A. Post-irradiation angiosarcoma of bone. J Can Res Ther [serial online] 2007 [cited 2021 Feb 28 ];3:96-99
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2007;volume=3;issue=2;spage=96;epage=99;aulast=Mittal;type=0