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Year : 2022  |  Volume : 18  |  Issue : 2  |  Page : 470-475

Image fusion technique for target volume delineation in 125I seed implant brachytherapy for parotid gland cancers

1 Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Haidian Dist, Beijing, People's Republic China
2 Department of Stomatology, Fujian Provincial Hospital, Gulou District, Fuzhou City, Fujian Province, People's Republic China

Correspondence Address:
Jie Zhang
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, 22 Zhongguancun South St, Beijing - 100081
People's Republic China
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcrt.jcrt_266_21

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Purpose: Variability in volume delineation is a possible error source in brachytherapy. This study assessed the interobserver variations in clinical target volume (CTV) delineation in postoperative adjuvant 125I seed implant brachytherapy after parotid gland cancer surgical resection and evaluated the image fusion technique for target volume delineation. Material and Methods: Five radiation oncologists delineated gross tumor volume (GTV) and CTV in 20 patients using conventional delineation and image fusion methods. The consistency in target volume delineation was determined on the basis of differences between the oncologists. Variability was determined using Kendall's W-test, the mean conformity index (CI), the mean distance to conformity (MDC), and the center of gravity distance (CGD). Results: There were significant variations in the delineated target volumes among radiation oncologists, but the CTV consistency was significantly enhanced using the image fusion technique, based on Kendall's W, mean CI, average MDC, and average CGD, which were 0.752, 0.41, 2.75, and 4.997, respectively, using the conventional method, and 0.987, 0.86, 0.55, and 1.27, respectively, using the image fusion method. Conclusions: The interobserver variation in the delineation of the postoperative parotid target volume is large, but it can be considerably decreased using image fusion technology, which resulted in a noticeable improvement in the delineation precision of the target volume for parotid gland cancer. Thus, this technology can enhance the efficacy of 125I seed implant brachytherapy and decrease any adverse effects induced by errors in target delineation.

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