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ORIGINAL ARTICLE
Year : 2021  |  Volume : 17  |  Issue : 4  |  Page : 917-924

Magnetic resonance imaging for the study of mediastinal adenopathies in lung cancer: Comparison with standard tests


1 Complejo Hospitalario Universitario de A Coruña, Departamento de Neumología, As Xubias, A Coruña, Madrid, Madrid, Spain
2 Complejo Hospitalario Universitario de Santiago de Compostela, Departamento de Radiología, A Choupana, Santiago de Compostela, Madrid, Madrid, Spain
3 Complejo Hospitalario Universitario de Santiago de Compostela, Departamento de Neumología, A Choupana, Santiago de Compostela; Grupo Interdisciplinar de Investigación en Neumología, Instituto Sanitario de Investigaciones en Santiago (IDIS), Santiago de Compostela, Madrid, Madrid, Spain
4 Complejo Hospitalario Universitario de Santiago de Compostela, Departamento de Neumología, A Choupana, Santiago de Compostela, Madrid, Madrid, Spain
5 Complejo Hospitalario Universitario de Santiago de Compostela, Departamento de Radiología, A Choupana, Santiago de Compostela, Madrid, Spain
6 Universidad de Santiago de Compostela, Departamento de Medicina Preventiva y Salud Pública, Santiago de Compostela; CIBER de Epidemiología y Salud Pública, Instituto de Salud Carlos III, Madrid, Madrid, Spain

Correspondence Address:
Tara Pereiro-Brea
University Hospital Complex, Pneumology Service, As Xubias, A Coruña 15006
Spain
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcrt.JCRT_1626_20

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Background: Lung cancer is the second most common cancer in both men and women. Mediastinal lymph node involvement in these patients, determined by imaging tests, indicates prognosis and modifies therapeutic attitude. Purpose: The aim of this study was to analyze the diagnostic capacity of magnetic resonance imaging (MRI) in the study of the mediastinum in comparison with conventional tests (computed tomography [CT] and positron-emission tomography [PET] or PET/CT scans), taking histology as the gold standard. Materials and Methods: An observational study was conducted on 16 patients with suspicion of primary lung cancer (June 2016 through December 2018). We studied their demographic characteristics and used CT, PET, or PET/CT scans and MRI (diffusion-weighted imaging-MRI sequence) to examine mediastinal disease and compare MRIs diagnostic yield and percentage agreement to that of conventional tests. Results: As compared to CT and PET scanning, MRI displayed a very low sensitivity and a specificity of 90 and 88%, respectively; positive predictive value was 0.67 (both) and negative predictive value (NPV) was 0.28 and 0.22, respectively. MRI showed a high degree of agreement in lymph node diagnosis when compared with histology (91.2%; P = 0.001): specificity in this case was high (E = 0.94), as was the NPV (NPV = 0.97). Conclusions: The results of this study would appear to indicate that MRI could play a relevant role in mediastinal staging of lung cancer. More prospective, multicenter studies are, however, needed to be able to draw up firm recommendations about the role of MRI and its place in lung cancer staging.


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