Lutetium therapy-induced carcinoid crisis: A case report and review of literature

Sanjay Kumar Yadav; Chandan Kumar Jha; Shrinivas Patil; Deepanksha Datta; Anjali Mishra; PK Pradhan

doi:10.4103/jcrt.JCRT_22_18

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Year : 2020 | Volume : 16 | Issue : 8 | Page : 206-208

Lutetium therapy-induced carcinoid crisis: A case report and review of literature

Sanjay Kumar Yadav¹, Chandan Kumar Jha¹, Shrinivas Patil², Deepanksha Datta³, Anjali Mishra¹, PK Pradhan⁴
¹ Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
² Medical Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
³ Department of Nuclear Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, India
⁴ Department of Nuclear Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

Correspondence Address:
Anjali Mishra
Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow - 226 014, Uttar Pradesh
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/jcrt.JCRT_22_18

Peptide receptor radionuclide therapy with ¹⁷⁷lutetium (Lu)-labeled somatostatin analogs is a promising new tool in the management of patients with inoperable or metastatic neuroendocrine tumors. Some of these patients may present with carcinoid syndrome and it is known that rarely carcinoid crisis can be precipitated by surgical or other interventions in these patients. However, there are anecdotal reports of carcinoid crisis after Lu-labeled peptide therapy. We are reporting our experience of successful management of one such case of carcinoid crisis which was precipitated by Lu therapy.

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