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REVIEW ARTICLE
Year : 2018  |  Volume : 14  |  Issue : 1  |  Page : 1-5

Mechanisms correlated with chemotherapy resistance in tongue cancers


1 Department of Oral Geriatrics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China
2 Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University, Changchun, China

Correspondence Address:
Dr. Dan Yu
Department of Otolaryngology Head and Neck Surgery, The Second Hospital, Jilin University, Changchun 130041
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcrt.JCRT_763_17

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Tongue cancer is one of the most common and deadly types of head and neck cancer. The incidence of tongue cancer has been particularly high and remained been increasing in some countries. A main reason for poor prognosis and clinical outcome for tongue cancer was its resistance to chemotherapies, behind which the mechanisms have been not clear. In this review, we summarized literatures published in recent years and listed the proteins, biomacromolecules, and signaling pathways related to this drug resistance. We hoped that this summary could provide reference for researchers to develop new treatment strategies for tongue cancer.


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