Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2018  |  Volume : 14  |  Issue : 10  |  Page : 730-735

Evaluation of the use of nab-paclitaxel and gemcitabine in clinical practice

Hospital Pharmacy Service, Estructura Organizativa de Gestión Integrada de Vigo – Hospital, Álvaro Cunqueiro, Vigo, Pontevedra, Spain

Correspondence Address:
Cristina Casanova-Martinez
Casanova-Martínez, Camiño dos Cañotais 44, 36212 Vigo, Pontevedra
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.188292

Rights and Permissions

Context: Pancreatic cancer in a common tumor in our country for which there are various treatment alternatives. Objective: Evaluate the effectiveness and safety of nab-paclitaxel and gemcitabine in everyday clinical practice. Settings and Design: Observational, retrospective study at a tertiary university hospital. Subjects and Methods: We included patients diagnosed of metastatic or locally advanced pancreatic cancer that were being treated with nab-paclitaxel and gemcitabine. We recorded response, progression-free survival (PFS), and overall survival (OS) rates together with toxicities. Statistical Analysis Used: We used SPSS program for Windows. We conducted descriptive statistics using averages, medians, standard deviations or ranges, and percentages. Results: We included 15 patients. At 3 months, there were no complete responses; 20% showed partial responses, and in 60% of patients, the disease stabilized. The median PFS was 8.9 months and the OS was 9.6. The most important adverse reactions were neutropenia, fatigue, and nausea/vomiting. Conclusions: The treatment regimen leads to increased survival in these patients with an acceptable toxicity profile.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded129    
    Comments [Add]    
    Cited by others 2    

Recommend this journal