Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2016  |  Volume : 12  |  Issue : 1  |  Page : 28-35

Seesaw of matrix metalloproteinases (MMPs)

1 Department of Oral Pathology and Microbiology, Bhojia Dental College, Baddi, Solan, India
2 Department of Prosthodontics and Implantology, Himachal Dental College, Sundernagar, Mandi, H.P, India
3 Department of Oral Pathology and Microbiology, Subharti Dental College, Meerut, U.P, India
4 Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, Haryana, India
5 Paradise Diagnostics, Delhi, India

Correspondence Address:
Charu Kapoor
Department of Oral Pathology and Microbiology, Bhojia Dental College, Budd, Baddi, Solan, Himachal Pradesh - 176 001
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.157337

Rights and Permissions

The family of human matrix metalloproteinases (MMPs) comprises several tightly regulated classes of proteases. These enzymes and their specific inhibitors play important roles in tumor progression and the metastatic process by facilitating extracellular matrix (ECM) degradation. As scientific understanding of the MMPs has advanced, therapeutic strategies focusing on blocking these enzymes by MMP inhibitors (MMPIs) have rapidly developed. This paper reviews MMPs in detail. Their perspectives in therapeutic intervention in cancer are also mentioned.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded492    
    Comments [Add]    

Recommend this journal