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Year : 2014  |  Volume : 10  |  Issue : 8  |  Page : 233-239

Updates in colorectal cancer stem cell research


1 Institute of Traditional Chinese Medicine Research, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193; Department of Emergency Medicine, Tianjin Chest Hospital, Tianjin 300060, China
2 Department of Editorial Office, Tianjin Huanhu Hospital, Tianjin 300060, China
3 Institute of Traditional Chinese Medicine Research, Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China

Correspondence Address:
Guan-Wei Fan
Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.151449

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Colorectal cancer (CRC) is one of the world most common malignant tumors, also is the main disease, which cause tumor-associated death. Surgery and chemotherapy are the most used treatment of CRC. Recent research reported that, cancer stem cells (CSCs) are considered as the origin of tumor genesis, development, metastasis and recurrence in theory. At present, it has been proved that, CSCs existed in many tumors including CRC. In this review, we summary the identification of CSCs according to the cell surface markers, and the development of drugs that target colorectal cancer stem cells.


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