Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2014  |  Volume : 10  |  Issue : 4  |  Page : 846-852

Cancer stem cells: An insight and future perspective


1 Department of Oral Medicine and Radiology, Adesh Institute of Dental Sciences and Research, Bathinda, Punjab, India
2 Department of Community Medicine, Adesh Institute of Medical Sciences and Research, Bathinda, Punjab, India
3 Department of Periodontology, Institute of Dental Studies and Technologies, Kadrabad, Modi Nagar, Uttar Pradesh, India

Correspondence Address:
Sandeep Kaur
Department of Oral Medicine and Radiology, Adesh Institute of Dental Studies and Research, Barnala Road, Bathinda, Punjab - 151 109
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.139264

Rights and Permissions

The cancer stem cell (CSC) concept derives from the fact that cancers are dysregulated tissue clones whose continued propagation is vested in a biologically distinct subset of cells that are typically rare. Rare CSCs have been isolated from a number of human tumors, including hematopoietic, brain, colon, and breast cancer. With the growing evidence that CSCs exist in a wide array of tumors, it is becoming increasingly important to understand the molecular mechanisms that regulate self-renewal and differentiation because corruption of genes involved in these pathways likely participates in tumor growth. Understanding the biology of CSCs will contribute to the identification of molecular targets important for future therapies.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed5973    
    Printed150    
    Emailed5    
    PDF Downloaded547    
    Comments [Add]    
    Cited by others 4    

Recommend this journal