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Year : 2014  |  Volume : 10  |  Issue : 2  |  Page : 374-376

Vimentin positive acantholytic penile squamous cell carcinoma with rhabdoid features

Department of Pathology and Surgery, KLE University's Jawaharlal Nehru Medical College, Belgaum, Karnataka, India

Correspondence Address:
Akshay Bali
Bali Clinic, Baldev Nagar, Ambala City, Haryana - 134 007
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.136662

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Acantholytic variant of penile squamous cell carcinoma (SCC) is an exceedingly rare and associated with bad prognosis. Histologically it mimics angiosarcoma due to pseudovascular spaces. Vimentin immunopositivity in such cases represent epithelial to mesenchymal transition manifested by cellular discohesion. We describe a case of vimentin positive acantholytic penile SCC in a 55-year-old patient.

Abstract in Chinese

阳性波形蛋白皮肤棘层松解型阴茎鳞状细胞癌伴横纹肌样特征 摘要 皮肤棘层松解型阴茎鳞状细胞癌是一种非常罕见的,预后不良的肿瘤。组织形态类似血管肉瘤因其假性脉管空间。波形蛋白免疫阳性反应,在这种情况下表现为上皮间质移行区的细胞不凝聚。本文报道一例55岁的阳性波形蛋白皮肤棘层松解型阴茎鳞状细胞癌病例。 关键词:皮肤棘层松解,阴茎,横纹肌,鳞状细胞癌,波形蛋白

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