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Year : 2014  |  Volume : 10  |  Issue : 1  |  Page : 147-152

Influence of the intravenous contrast media on treatment planning dose calculations of lower esophageal and rectal cancers

1 Solid Tumor Research center, Urmia University of Medical Sciences; Department of Medical Physics and Imaging, University of Medical Sciences, Urmia, Iran
2 Radiotherapy Center of the Omid Hospital, Urmia, Iran
3 Radiology Center of the Imam Reza Hospital, Urmia, Iran
4 Department of Medical Physics and Imaging, University of Medical Sciences, Urmia, Iran

Correspondence Address:
Zeinali Ahad
Department of Medical Physics and Imaging, Urmia University of Medical Sciences, Urmia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.131465

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Background: The impact of intravenous (IV) contrast media (CM) on radiation dose calculations must be taken into account in treatment planning. Purpose: The aim of this study is to evaluate the effect of an intravenous contrast media on dose calculations in three-dimensional conformal radiation therapy (3D-CRT) for lower esophageal and rectal cancers. Materials and Methods: Seventeen patients with lower esophageal tumors and 12 patients with rectal cancers were analyzed. At the outset, all patients were planned for 3D-CRT based on the computed tomography (CT) scans with IV contrast media. Subsequently, all the plans were copied and replaced on the scans without intravenous CM. The radiation doses calculated from the two sets of CTs were compared. Results: The dose differences between the planning image set using intravenous contrast and the image set without contrast showed an average increase in Monitor Units (MUs) in the lower esophageal region that was 1.28 and 0.75% for 6 and 15 MV photon beams, respectively. Conclusion: There was no statistical significant difference in the rectal region between the two sets of scans in the 3D-CRT plans. The results showed that the dose differences between the plans for the CT scans with and without CM were small and clinically tolerable. However, the differences in the lower esophageal region were significant in the statistical analysis.

Abstract in Chinese

静脉造影剂对下段食管癌和直肠癌治疗计划剂量计算的影响 背景:在治疗计划中必须考虑静脉注射造影剂的辐射剂量计算。 目的:本研究的目的是评估静脉注射造影剂在食管下段癌和直肠癌三维适形放疗(3D-CRT)剂量计算中的影响。 材料和方法:对17例食管下段癌和12例直肠癌病例进行分析。在一开始,所有患者的三维适形计划均基于注射了静脉造影剂后的CT扫描。随后,所有的计划都被复制,并由无静脉造影剂CT扫描替换。将两套CT得出的辐射剂量计算进行比较。 结果:食管下端区域使用静脉造影剂和不使用静脉造影剂的计划图像的剂量差,在监视器上表现的平均增长分别为: 1.28%(6MV光子束)和0.75%(15 MV光子束)。 结论:两组扫描在直肠区域三维适形放疗计划中无统计学显著差异。结果表明,使用和不使用静脉造影剂CT扫描计划的剂量之间的差异小,临床上可接受。然而,在统计分析中,食管下端区域的差异明显。 关键词:造影剂,食管和直肠癌,治疗计划

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