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Year : 2013  |  Volume : 9  |  Issue : 3  |  Page : 529-531

Osteoid differentiation in mesodermal (mullerian) adenosarcoma of ovary

Department of Pathology, Gujarat Cancer and Research Institute, M.P. Shah Cancer Hospital, Ahmedabad, Gujarat, India

Correspondence Address:
Trupti Patel
Room # 412, Department of Pathology, The Gujarat Cancer and Research Institute, NCH Campus, Asarwa, Ahmedabad, Gujarat State
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.119371

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A 55-year-old female presented with abdominal pain and 10 cm mass per abdominal examination. Computerized tomography scan of abdomen and pelvis revealed a heterogeneously enhancing solid cystic mass right ovarian mass and mild ascites. Surgery was performed. Specimens were sent for examination. Microscopic examination revealed an admixture of benign but occasionally atypical appearing mullerian type glands with sarcomatous stroma. Solid area showed undifferentiated tumour cells. Atypical mitoses and necrosis were also seen. Areas with extensive benign osteoid surrounded by fibroblastic stroma were also present. Glandular component showed positivity for CK-7, AE-1 and EMA while sarcomatous areas showed positivity for vimentin only. Mullerian adenosarcoma of ovary with sarcomatous overgrowth (SO) having heterologous component was confirmed. Postoperative 3 cycles of chemotherapy was given and the patient was well till date (three months after surgery).

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