| CORRESPONDENCE |
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| Year : 2013 | Volume
: 9
| Issue : 2 | Page : 284-286 |
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Low-grade myofibroblastic sarcoma of the larynx: A rare entity with review of literature
Divya Khosla1, Budhi Singh Yadav1, Ritesh Kumar1, Sushmita Ghoshal1, Kim Vaiphei2, Roshan Verma3, Suresh C Sharma1
1 Department of Radiotherapy and Oncology, Regional Cancer Centre, Chandigarh, India
2 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Otolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Correspondence Address:
Budhi Singh Yadav
Department of Radiotherapy and Oncology, Regional Cancer Centre, Post Graduate Institute of Medical Education & Research (PGIMER), Sector 12, Chandigarh - 160012
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0973-1482.113387
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Mesenchymal neoplasms of the larynx are rare and make up approximately 0.3% to 1.0% of all malignancies at this location. Low grade myofibroblastic sarcoma (LGMS) of larynx is a rare entity. We describe a rare case of LGMS of larynx who presented with complaint of hoarseness of voice. The patient was treated with total laryngectomy plus partial pharyngectomy followed by post-operative radiotherapy. Histopathologically, the lesion was composed of spindle cells that manifested variable cellular anaplasia and expressed smooth muscle actin (SMA) and focally S-100.One of the resection limits was involved so patient was given post-operative radiotherapy. The patient is alive and disease free 14 months after surgery. The characteristic clinical, histopathological features and treatment of this case are described with a literature review. |
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