Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2012  |  Volume : 8  |  Issue : 6  |  Page : 67-71

The role of intensity modulated radiotherapy in advanced oral cavity carcinoma

1 Head and Neck Unit, Royal Marsden Hospital, SW3 6JJ; The Institute of Cancer Research, 237 Fulham Road, SW3 6JB, London, United Kingdom
2 Head and Neck Unit, Royal Marsden Hospital, SW3 6JJ, London, United Kingdom

Correspondence Address:
S A Bhide
Head and Neck Unit, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT
United Kingdom
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.92218

Rights and Permissions

It is increasingly being recognized that oral cavity cancer incidences are rising globally. Furthermore, these tumors represent a high risk group of tumors comparative to other head and neck tumor sub-sites and have a high preponderance of occult nodal metastases. Surgery alone leads to excellent outcomes in early stage disease. Advanced tumors require adjuvant radiotherapy with or without concomitant chemotherapy. Irradiation using 3D conformal radiotherapy results in high incidence of late radiation side-effects. Xersostomia and mandibular osteoradionecrosis result in most significant effects on patients' quality of life. Intensity modulated radiotherapy (IMRT) is an advanced approach to 3-D treatment planning and conformal therapy (3D-CRT). It optimizes the delivery of irradiation to irregularly-shaped volumes and has the ability to produce concavities in radiation treatment volumes and hence enables sparing of normal tissue while delivering adequate doses to the tumor volumes. In this manuscript, we discuss the advantages of IMRT based on review of published peer reviewed literature.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded431    
    Comments [Add]    
    Cited by others 6    

Recommend this journal