ANALYTICAL REPORT |
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Year : 2012 | Volume
: 8
| Issue : 2 | Page : 306-307 |
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Follicular dendritic cell sarcoma: A diagnostic challenge !
Ajay Malik1, Ajit Veniyoor2, Barnard Fanthome3, Vibha Dutta1
1 Department of Pathology, AFMC, Pune, India 2 Medical Oncologist, Oman 3 Consultant Onco-Surgery, Mumbai, India
Correspondence Address:
Ajay Malik Department of Pathology, AFMC, Pune India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0973-1482.98998
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Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cells origin. It is known to occur in lymph nodes and rarely has been reported in extranodal tissues like head and neck, mediastinum and gastrointestinal tract. We herein report the first FDCS arising from anal canal in a 56-year-old man. The tumor was composed of bland short spindle cells in focal whorl formation with interspersed few lymphocytes. The tumor cells were classically positive for CD21, CD23, CD35 and vimentin. Despite its misleading morphology, immunohistochemistry helped us to reach a conclusive diagnosis for relevant therapy. |
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