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Year : 2010  |  Volume : 6  |  Issue : 3  |  Page : 394-396

Radiation-induced chondrosarcomas: A case report with review of literature

Department of Histopathology, Rajiv Gandhi Cancer Institute & Research Centre, Rohini, Delhi, India

Correspondence Address:
J S Gandhi
C-2-C/12/58, Janak Puri, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.73340

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Radiation therapy has become an important component of various cancer treatments. The development of second malignancy as a result of radiation therapy is a well-known sinister complication. However, radiation-induced sarcomas (RIS) are rare complications of radiation therapy. The timescale between completion of the radiotherapy and the development of a second malignancy, known as the latent period, can vary widely from as little as 5 years to 50 years later. Radiation-induced sarcomas per se are very rare and those with histomorphology of chondrosarcomas are even rarer. We report a rare case of RIS of left iliac bone in a 62-year-old lady after combined chemotherapy and external beam radiation therapy for cervical carcinoma (stage IIb). This case is being reported for its extreme rarity, vivid histology and clinical presentation.

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