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Year : 2010  |  Volume : 6  |  Issue : 3  |  Page : 344-346

Rituximab-induced subacute interstitial pneumonitis: A case report and review of literature

1 Department of Medical Oncology, M. S. Ramaiah Medical College, Bangalore - 560 054, India
2 Department of General Medicine, M. S. Ramaiah Medical College, Bangalore - 560 054, India
3 Department of Chest diseases, M. S. Ramaiah Medical College, Bangalore - 560 054, India

Correspondence Address:
Murali Subramanian
Department of Medical Oncology, M.S. Ramaiah Medical College, MSRIT post, Bangalore - 560 054
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.73356

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Rituximab is a chimeric anti-CD20 monoclonal antibody used to treat CD20+ non-Hodgkin's lymphoma (NHL). Some pulmonary adverse reactions such as cough, rhinitis, bronchospasm and dyspnea are relatively common. Severe respiratory conditions like cryptogenic organizing pneumonia, interstitial pneumonitis have rarely been reported. We present a case of interstitial pneumonitis in a patient who was treated with R-CHOP for extranodal NHL. He responded to the steroids.

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