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ORIGINAL ARTICLE
Year : 2010  |  Volume : 6  |  Issue : 3  |  Page : 267-271

Mapping the extent of disease by multislice computed tomography, magnetic resonance imaging and sentinel node evaluation in stage I and II cervical carcinoma


1 Department of Obstetrics & Gynaecology, University College of Medical Sciences & Guru Teg Bahadur Hospital (UCMS & GTBH), Delhi, India
2 Department of Radiodiagnosis, University College of Medical Sciences & Guru Teg Bahadur Hospital (UCMS & GTBH), Delhi, India
3 Division of Radiological Imaging & Bioinformatics, Institute of Nuclear Medicine & Allied Sciences (INMAS), Delhi, India

Correspondence Address:
S Rajaram
Department of Obstetrics & Gynaecology, University College of Medical Sciences & Guru Teg Bahadur Hospital, Delhi-110095
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1482.73342

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Aims: (1) To map the extent of disease in women with stage I and II carcinoma cervix by multislice spiral computed tomography (CT), magnetic resonance imaging (MRI) and sentinel nodes. (2) To assess accuracy of each modality individually and in conjunction with FIGO clinical staging. Design and Setting: Prospective, single-blind study. Departments of Obstetrics and Gynaecology, Radiodiagnosis, and Pathology, UCMS and GTBH and Division of Radiological Imaging and Bioinformatics, INMAS, Delhi. Material and Method: The study was conducted on 25 women with cervical cancer FIGO stage I and II. Each woman underwent clinical staging, multislice spiral CT and MRI which was compared to the gold-standard histopathology/cytology. The overall accuracy of each modality and improvement of clinical staging by CT/MRI were noted. Sentinel nodes were evaluated by intracervical Patent Blue V dye injection. Statistical Analysis: Sensitivity, specificity, positive and negative predictive values were calculated by 2Χ2 contingency tables. Results: The accuracy of staging by FIGO, CT and MRI was 68%, 52% and 80%, respectively. MRI and CT improved the overall accuracy of FIGO staging to 96% and 80%, respectively. Sentinel nodes were identified in 89% of patients with 91% accuracy. Conclusion: MRI emerges as the most valuable stand-alone modality improving accuracy of FIGO staging to 96%. Sentinel lymph-node evaluation appears promising in evaluating spread beyond cervix.


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