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Year : 2009  |  Volume : 5  |  Issue : 1  |  Page : 8-13

Long-term results of LINAC-based stereotactic radiosurgery for acoustic neuroma: The Greek experience

1 Radiotherapy Unit, Medical School, National University of Athens, Greece
2 Department of Medical Physics, St Savvas Anticancer Hospital, Athens, Greece
3 Department of Radiotherapy, Alexandras General Hospital, Athens, Greece

Correspondence Address:
Maria-Aggeliki Kalogeridi
12 Karaiskaki, St. GR-15562, Holargos
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.48764

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Purpose: To estimate the value of LINAC-based stereotactic radiosurgery (SRS) for the long-term local control of unilateral acoustic neuromas. Materials and Methods: Twenty patients (median age 66; range 57-80 years) with unilateral acoustic neuroma underwent LINAC-based SRS from May 2000 through June 2004 with a dose of 11-12 Gy. The follow-up period ranged from 36 to 84 months (median follow-up period: 55 months). Before SRS none of the patients had useful hearing. The follow-up consisted of repeat imaging studies and clinical examination for assessment of facial and trigeminal nerve function at 6-month intervals for the first year and yearly thereafter. Results: Eleven tumors (58%) decreased in size and eight (42%) remained stable. One tumor showed a minor increase in size on the MRI done 6 months after SRS in comparison with the pretreatment MRI; however, a subsequent decrease was noticed on the next radiographic assessment and the tumor remained stable from then on. None of the tumors increased in size in the long-term follow-up, thus giving an overall growth control of 100% for the patients in this study. None of the patients had useful hearing before SRS, so hearing level was not assessed during follow-up. No patient developed new, permanent facial or trigeminal neuropathy. Conclusion: LINAC-based SRS with 11-12 Gy provides excellent tumor control in acoustic neuroma and has low toxicity even after long-term follow-up.

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