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Year : 2008  |  Volume : 4  |  Issue : 4  |  Page : 203-205

Lymphoma of frontotemporal region with massive bone destruction and intracranial and intraorbital extension

1 Department of Surgery, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha, India
2 Department of Pathology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal

Correspondence Address:
Amit Agrawal
Division of Neurosurgery, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha- 442 004, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.44294

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Primary non-Hodgkin's lymphoma with unilateral proptosis and diffuse involvement of the craČnial vault and brain parenchyma is extremely rare. A 50-year-old woman developed a progressively increasing proptosis of her right eye, associated with a subcutaneous mass over the right frontotemporal region over the last 5 months. CT scan showed a high-density contrast-enhancing lesion with wide involvement of the cranium and intracranial and intraorbital extension. We performed a wedge biopsy for further analysis. Histological examination revealed that the tumor was non-Hodgkin's lymphoma. There was no evidence of systemic involvement. The patient received radiotherapy and was doing well at 18 months' follow-up. Primary malignant lymphoma involving the orbit and cranial vault is a rare malignancy, and treatment remains to be defined.

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