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Year : 2008  |  Volume : 4  |  Issue : 3  |  Page : 140-143

Suprasellar ganglioglioma with unusual diffuse involvement of the entire optico-chiasmal hypothalamic pathway

Departments of Radiation Oncology and Pathology, Tata Memorial Hospital, Mumbai and Neurosurgery, BJ Wadia Hospital, Mumbai, India

Correspondence Address:
Rakesh Jalali
125, Tata Memorial Hospital, Parel, Mumbai- 400 012
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.43151

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Gangliogliomas (GG) are mixed glioneuronal tumors of the central nervous system (CNS), occurring mostly in the pediatric population, with common sites being temporal lobes and less commonly in the frontal and parietal lobes. We report a case of a 7-year-old child who presented with bilateral visual defects for 6 months. Magnetic resonance imaging (MRI) of the brain revealed an intensely enhancing mass lesion with calcification in the sellar and suprasellar region involving the optic chiasm and the left optic nerve. The mass showed almost bilaterally symmetrical diffuse spread along the optic tracts posteriorly and hypothalamus, temporal lobes, thalami and the basal ganglia. The lesion was radiologically indistinguishable from chiasmatic astrocytoma or a germ cell tumor but histopathological features were of a ganglioglioma. While a few optic apparatus gangliogliomas have been reported in the literature, such widespread diffuse involvement of the entire optico-chiasmal hypothalamic pathway is unusual.

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