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Year : 2006  |  Volume : 2  |  Issue : 4  |  Page : 200

Squamous cell carcinoma over a nevus: A rare case

Acharya Harihar Regional Cancer Centre, Cuttack, Orissa, India

Correspondence Address:
K C Patro
SR-I, Dept of Radiation Oncology, Tata Memorial Hospital, Dr. E. Borges Marg, Parel, Mumbai
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.29831

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 > Abstract 

Malignant melanoma and basal cell carcinoma are more common over a preexisting nevus. But squamous cell carcinoma over a nevus is a rare phenomenon. A 55-year-old male presented with a slow growing noduloulcerative lesion on a preexisting nevus over scalp. For that he had undergone excisional biopsy. Biopsy came out to be a squamous cell carcinoma with lateral margin positive for tumor. So postoperative radiotherapy given by means of HDR brachytherapy. Now he is on follow-up.

Keywords: Nevus, squamous cell carcinoma

How to cite this article:
Patro K C, Padhi S, Singh D N. Squamous cell carcinoma over a nevus: A rare case. J Can Res Ther 2006;2:200

How to cite this URL:
Patro K C, Padhi S, Singh D N. Squamous cell carcinoma over a nevus: A rare case. J Can Res Ther [serial online] 2006 [cited 2021 May 7];2:200. Available from: https://www.cancerjournal.net/text.asp?2006/2/4/200/29831

 > Introduction Top

Among the various cutaneous malignancies, basal cell carcinoma out numbers melanoma and squamous histology. They mainly arise from sun exposure area particularly scalp and face. Malignant melanoma and basal cell carcinoma are two conditions can occur in preexisting nevus. Squamous histology is very rare over a preexisting nevus. There are no earlier reports on this and also no material available in books.

 > Case report Top

A 55-year-old male presented with an ulceronodular lesion over a preexisting nevus at the Regional Cancer Centre, Cuttack. Gross examination revealed a 2x2 cm dimension of noduloulcerative lesion over a nevus of 4x5 cm dimension on scalp. According to the patient, the nevus was small in size but gradually increasing in all directions in the last one yr to reach the existing new size. But the patient noticed a ulceronodular lesion in the last one month over central part of the growing nevus. That initiated the patient to meet the physician. Then he had undergone local excision of that noduloulcerative lesion but no treatment to nevus on histology. It came out to be a squamous cell carcinoma with lateral margin positive of tumor. For that patient treated with postoperative radiotherapy by means of HDR brachytherapy of total dose 59 Gy LDR equivalent @ 3Gy/ fraction and 2 fractions per day at 6h interval. Now the patient is on follow-up.

 > Discussion Top

The present case report reveals an unusual presentation.

Malignant melanoma occurs in preexisting nevus like common nevi,[1] atypical nevi,[2] dysplastic nevi,[3] congenital nevi.[4] But no case reports have been reported about squamous cell carcinoma over a nevus. There is also no book data available till date.

Though malignant melanoma and basal cell carcinoma are reported over preexisting nevus. After the reporting of this case one should not overlook the squamous histology over a nevus.

 > References Top

1.Lotze MT, Heyward N. Personal communication 2000.  Back to cited text no. 1
2.Norduland JJ, Kirkwood J, Forget BM, Scheibner A, Albert DM, Lerner E, et al . Demographic study of clinically atypical (dysplastic) nevi in patients with melanoma and comparison subjects. Cancer Res 1985;45:1855-61.  Back to cited text no. 2
3.Elder DE, Goldman LI, Goldman SC, Greene MH, Clark WH Jr. Dysplastic nevus syndrome: A phenotypic association of sporadic cutaneous melanoma. Cancer 1980;46:1787-94.  Back to cited text no. 3
4.Tuker MA, Halpern A, Holly EA, Hartge P, Elder DE, Sagebiel RW, et al. Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma. JAMA 1997;277:1439-44.   Back to cited text no. 4


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