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Figure 2: Effect of FL34 on the invasion of glioblastoma cells and the tube formation of HUVEC-T cells in vitro. (a and b) Equal numbers of U-87 MG (ai and ii) and T98G (bi and ii) cells were seeded into the upper compartment of a Transwell system and allowed to invade through the Matrigel for 14 h. The invaded cells were fixed and counted. Decreased invasion is observed cells treated with FL34 compared to that in control cells. The error bars represent the standard deviation. *P < 0.05 and **P < 0.01 versus control cells. (c) Tube formation assay. The tube formation of HUVEC-T cells was inhibited following the administration of FL34 for 5 h. (ci) Representative pictures are presented; (cii) The results of total tubule length are shown as quantitative bar graphs, the error bars represent the standard deviation. *P < 0.05, **P < 0.01, ***P < 0.001, versus control cells

Figure 2: Effect of FL34 on the invasion of glioblastoma cells and the tube formation of HUVEC-T cells <i>in vitro</i>. (a and b) Equal numbers of U-87 MG (ai and ii) and T98G (bi and ii) cells were seeded into the upper compartment of a Transwell system and allowed to invade through the Matrigel for 14 h. The invaded cells were fixed and counted. Decreased invasion is observed cells treated with FL34 compared to that in control cells. The error bars represent the standard deviation. *<i>P</i> < 0.05 and **<i>P</i> < 0.01 versus control cells. (c) Tube formation assay. The tube formation of HUVEC-T cells was inhibited following the administration of FL34 for 5 h. (ci) Representative pictures are presented; (cii) The results of total tubule length are shown as quantitative bar graphs, the error bars represent the standard deviation. *<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001, versus control cells