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Figure 2: Proposed mechanism for molecular metastatic cascade in MA. EMT-Epithelial mesenchymal transition, RAC-Rho family of GTPases, MAPK-Mitogen activated protein kinase,EGF-Endothelial growth factor, MMPs-Matrix metalloproteinases, TGF-1α-Transforming growth factor, VE-Vascular endothelial

Figure 2: Proposed mechanism for molecular metastatic cascade in MA. EMT-Epithelial mesenchymal transition, RAC-Rho family of GTPases, MAPK-Mitogen activated protein kinase,EGF-Endothelial growth factor, MMPs-Matrix metalloproteinases, TGF-1α-Transforming growth factor, VE-Vascular endothelial