Journal of Cancer Research and Therapeutics Close
 

Figure 3: Statistically significant differential promoter methylation of tumor suppressor genes. (a) Bar diagram showing statistically significant (P ≤ 0.05) differentially methylated genes, that is, WT1 (Wilms tumor 1), TERT (telomerase reverse transcriptase), NEUROG1 (neurogenin 1), OPCML (opioid binding protein/cell adhesion molecule-like), SCGB3A1 (Secretoglobin, family 3A, member 1), CDH1 (Cadherin 1, type 1, E-cadherin [epithelial]), THBS1 (thrombospondin 1), and VEGFA (vascular endothelial growth factor a) between tumor and adjacent normal tissue. Blue bars represent normal and orange bars signify tumor tissues. The X-axis denotes the name of genes and Y-axis represents the mean of percentage of hypermethylation (error bars showing standard deviation of mean). (b) Bar diagram showing fold change in methylation. Orange-colored bars are showing fold upregulation in methylation and blue bars are displaying fold down-regulation

Figure 3: Statistically significant differential promoter methylation of tumor suppressor genes. (a) Bar diagram showing statistically significant (<i>P</i> ≤ 0.05) differentially methylated genes, that is, WT1 (Wilms tumor 1), TERT (telomerase reverse transcriptase), NEUROG1 (neurogenin 1), OPCML (opioid binding protein/cell adhesion molecule-like), SCGB3A1 (Secretoglobin, family 3A, member 1), CDH1 (Cadherin 1, type 1, E-cadherin [epithelial]), THBS1 (thrombospondin 1), and VEGFA (vascular endothelial growth factor a) between tumor and adjacent normal tissue. Blue bars represent normal and orange bars signify tumor tissues. The X-axis denotes the name of genes and Y-axis represents the mean of percentage of hypermethylation (error bars showing standard deviation of mean). (b) Bar diagram showing fold change in methylation. Orange-colored bars are showing fold upregulation in methylation and blue bars are displaying fold down-regulation