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Figure 4: TZD18 exposure modulated the mitochondrial membrane potential and the release of cytochrome c in MKN-45 cell. (a) Mitochondrial membrane potential damage was evaluated using JC-1 reagent using flow cytometric analysis. (b) The results are presented as means ± standard deviation of three independent experiments (*P < 0.05). (c) Fluorescent photomicrograph of mitochondrial (Green) and cytochrome c (Red) translocation treated by 12.5 and 50 μM TZD18 for 72 h

Figure 4: TZD18 exposure modulated the mitochondrial membrane potential and the release of cytochrome c in MKN-45 cell. (a) Mitochondrial membrane potential damage was evaluated using JC-1 reagent using flow cytometric analysis. (b) The results are presented as means ± standard deviation of three independent experiments (*<i>P</i> < 0.05). (c) Fluorescent photomicrograph of mitochondrial (Green) and cytochrome c (Red) translocation treated by 12.5 and 50 μM TZD18 for 72 h