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Figure 2: TZD18 could induce cell apoptosis in MKN-45 cells. (a) Cells were treated with 50 μM TZD18 for 72 h, fixed, stained with 4, 6-diamidino-2-phenylindole and stained nuclei, and observed under a fluorescent microscope. (b) Cells treated with 0, 12.5, 25, and 50 μM TZD18 for 24, 48, and 72 h were assessed for apoptosis by staining with Annexin V-FITC and propidium iodide. (c) The apoptosis percentage of cells treated with 0, 12.5, 25, and 50 μM TZD18 for 24, 48, and 72 h were assessed for apoptosis by staining with Annexin V-FITC and propidium iodide. *P < 0.05, compared with control

Figure 2: TZD18 could induce cell apoptosis in MKN-45 cells. (a) Cells were treated with 50 μM TZD18 for 72 h, fixed, stained with 4, 6-diamidino-2-phenylindole and stained nuclei, and observed under a fluorescent microscope. (b) Cells treated with 0, 12.5, 25, and 50 μM TZD18 for 24, 48, and 72 h were assessed for apoptosis by staining with Annexin V-FITC and propidium iodide. (c) The apoptosis percentage of cells treated with 0, 12.5, 25, and 50 μM TZD18 for 24, 48, and 72 h were assessed for apoptosis by staining with Annexin V-FITC and propidium iodide. *<i>P</i> < 0.05, compared with control