Journal of Cancer Research and Therapeutics Close
 

Figure 3: Trial sequential analysis on effectiveness on transdermal fentanyl. Trial sequential analysis on effectiveness on transdermal fentanyl, of 29 randomized controlled trials (marked with black dots) illustrated that the cumulative Z-curve crossed the required information size after four trials, and the required information size was calculated to 174 (the vertical line). (NOTE: The red line is the trial sequential analysis monitor boundary according to a relative risk reduction of 20%, type I error of 5% and type II error of 20%. The red horizontal line is the Z-score of ± 1.96, equal to two-sided P = 0.05. X-axis: The number of patients randomized, Y-axis: The Z-score)

Figure 3: Trial sequential analysis on effectiveness on transdermal fentanyl. Trial sequential analysis on effectiveness on transdermal fentanyl, of 29 randomized controlled trials (marked with black dots) illustrated that the cumulative Z-curve crossed the required information size after four trials, and the required information size was calculated to 174 (the vertical line). (NOTE: The red line is the trial sequential analysis monitor boundary according to a relative risk reduction of 20%, type I error of 5% and type II error of 20%. The red horizontal line is the Z-score of ± 1.96, equal to two-sided <i>P</i> = 0.05. X-axis: The number of patients randomized, Y-axis: The Z-score)