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Figure 2: Comparison of Mini-Mental State Examination and Montreal Cognitive Assessment scores, S-100 β protein level in Group M + P, Group M + S, Group D + P, and Group D + S. Mini-Mental State Examination and Montreal Cognitive Assessment scores were used to assess the cognitive function at the day before operation (Ts), the 1st (Tb), 3rd (Tc), and 7th (Td) day after operation, and S-100 β protein level was used to reflect the level of brain injury at 10 min before anesthesia (Ta), the 1st (Tb), 3rd (Tc), and 7th (Td) day after operation in different groups. (a and b) Mini-Mental State Examination and Montreal Cognitive Assessment scores in different groups. Compared with Group M + P at Tb, Tc, and Td, #P < 0.05 in Group M + S; Compared with Group M + S at Tb, Tc, and Td, *P < 0.05 in Group D + S. (c) S-100 β protein level in different groups. Compared with Group M + P at Tb, Tc, and Td, #P < 0.05 in Group M + S; Compared with Group M + S at Tb, Tc, and Td, *P < 0.05 in Group D + S. Data are representative of 30 independent experiments

Figure 2: Comparison of Mini-Mental State Examination and Montreal Cognitive Assessment scores, S-100 β protein level in Group M + P, Group M + S, Group D + P, and Group D + S. Mini-Mental State Examination and Montreal Cognitive Assessment scores were used to assess the cognitive function at the day before operation (Ts), the 1<sup>st</sup> (Tb), 3<sup>rd</sup> (Tc), and 7<sup>th</sup> (Td) day after operation, and S-100 β protein level was used to reflect the level of brain injury at 10 min before anesthesia (Ta), the 1<sup>st</sup> (Tb), 3<sup>rd</sup> (Tc), and 7<sup>th</sup> (Td) day after operation in different groups. (a and b) Mini-Mental State Examination and Montreal Cognitive Assessment scores in different groups. Compared with Group M + P at Tb, Tc, and Td, <sup>#</sup><i>P</i> < 0.05 in Group M + S; Compared with Group M + S at Tb, Tc, and Td, *<i>P</i> < 0.05 in Group D + S. (c) S-100 β protein level in different groups. Compared with Group M + P at Tb, Tc, and Td, <sup>#</sup><i>P</i> < 0.05 in Group M + S; Compared with Group M + S at Tb, Tc, and Td, *<i>P</i> < 0.05 in Group D + S. Data are representative of 30 independent experiments