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Figure 3: Role of miR-27a in H1650 proliferation, migration, and invasion. (a) Growth curves of H1650 PLKO.1 and H1650 miR-27a cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. (b) Xenografts of H1650 miR-27a cells showing increased growth compared with H1650 PLKO.1 cells on day 21. (c) Scratch tests analyzed at 0 or 24 h in H1650 PLKO.1 and H1650 miR-27a cell lines. Data are presented as the mean ± standard deviation (n = 3). (d) Transwell invasion assay of H1650 PLKO.1 and H1650 miR-27a cells. Data are presented as the mean ± standard deviation (n = 5), ***P < 0.001

Figure 3: Role of miR-27a in H1650 proliferation, migration, and invasion. (a) Growth curves of H1650 PLKO.1 and H1650 miR-27a cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. (b) Xenografts of H1650 miR-27a cells showing increased growth compared with H1650 PLKO.1 cells on day 21. (c) Scratch tests analyzed at 0 or 24 h in H1650 PLKO.1 and H1650 miR-27a cell lines. Data are presented as the mean ± standard deviation (<i>n</i> = 3). (d) Transwell invasion assay of H1650 PLKO.1 and H1650 miR-27a cells. Data are presented as the mean ± standard deviation (<i>n</i> = 5), ***<i>P</i> < 0.001