Journal of Cancer Research and Therapeutics Close
 

Figure 1: The expression level of plasma miR-185 was specifically correlated with glioma. (a) Plasma level of miR-185 in normal cohorts, meningioma cohorts, pituitary adenoma cohorts, acoustic neurinoma and glioma cohorts. miR-185 was normalized to cel-miR-39 and cel-miR-238 and analyzed using 2-ΔΔCT method. Statistically significant differences were determined using the Mann-Whitney U-test. Data were represented as mean ± standard deviation (SD) from three independent experiments. **P < 0.01. (b) miR-185 expression level in plasma of healthy controls (n = 20), glioma I + II (n = 23) and glioma IV + III (n = 43) patients. miR-185 was normalized to cel-miR-39 and cel-miR-238 and analyzed using 2-ΔΔCT method. Statistically significant differences were determined using the Mann-Whitney U-test. Data were represented as mean ± SD from three independent experiments. *P < 0.05, **P < 0.01. (c) The miR-185 expression in preoperation (n = 19), postoperation (n = 19), and chemo-radiation (n = 19) plasma samples. miR-185 is normalized to cel-miR-39 and cel-miR-238 and analyzed using 2-ΔΔCT method. Statistically significant differences were determined using the Mann-Whitney U-test. Data were represented as mean ± SD from three independent experiments **P < 0.01

Figure 1: The expression level of plasma miR-185 was specifically correlated with glioma. (a) Plasma level of miR-185 in normal cohorts, meningioma cohorts, pituitary adenoma cohorts, acoustic neurinoma and glioma cohorts. miR-185 was normalized to cel-miR-39 and cel-miR-238 and analyzed using 2-ΔΔCT method. Statistically significant differences were determined using the Mann-Whitney U-test. Data were represented as mean ± standard deviation (SD) from three independent experiments. **<i>P</i> < 0.01. (b) miR-185 expression level in plasma of healthy controls (<i>n</i> = 20), glioma I + II (<i>n</i> = 23) and glioma IV + III (<i>n</i> = 43) patients. miR-185 was normalized to cel-miR-39 and cel-miR-238 and analyzed using 2-ΔΔCT method. Statistically significant differences were determined using the Mann-Whitney U-test. Data were represented as mean ± SD from three independent experiments. *<i>P</i> < 0.05, **<i>P</i> < 0.01. (c) The miR-185 expression in preoperation (<i>n</i> = 19), postoperation (<i>n</i> = 19), and chemo-radiation (<i>n</i> = 19) plasma samples. miR-185 is normalized to cel-miR-39 and cel-miR-238 and analyzed using 2-ΔΔCT method. Statistically significant differences were determined using the Mann-Whitney U-test. Data were represented as mean ± SD from three independent experiments **<i>P</i> < 0.01