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Figure 5: Well-differentiated carcinoma (a) showing elongated nuclei, scanty cytoplasm, wide intercellular spaces (ICS) and clumping of tonofilaments ×3000, tubular mitochondria (b) ×45,000, Keratinization (k) (c) ×20,000, tonofilaments (d) ×3000 and desmosomal (d) alterations with widened ICS (e) ×4500 in oral squamous cell carcinoma patients. (f) showing degenerative, necrotic changes with irregular NM ×7000, swollen and irregular mitochondria (M) (g) ×45,000, dilated endoplasmic reticulum (ER) (h) ×10,000 and less keratinization (K) (i) ×10,000 in relocation time (RT) patients. (j) showing pleomorphic nucleus (n) with altered nucleus to cytoplasmic ratio, cytoplasmic granules, condensed chromatin, less dense intercellular junctions ×4500, globular ER, absence of keratinization (k) ×15,000 and microfilaments (l) ×15,000 in RT + selenium supplemented patients

Figure 5: Well-differentiated carcinoma (a) showing elongated nuclei, scanty cytoplasm, wide intercellular spaces (ICS) and clumping of tonofilaments ×3000, tubular mitochondria (b) ×45,000, Keratinization (k) (c) ×20,000, tonofilaments (d) ×3000 and desmosomal (d) alterations with widened ICS (e) ×4500 in oral squamous cell carcinoma patients. (f) showing degenerative, necrotic changes with irregular NM ×7000, swollen and irregular mitochondria (M) (g) ×45,000, dilated endoplasmic reticulum (ER) (h) ×10,000 and less keratinization (K) (i) ×10,000 in relocation time (RT) patients. (j) showing pleomorphic nucleus (n) with altered nucleus to cytoplasmic ratio, cytoplasmic granules, condensed chromatin, less dense intercellular junctions ×4500, globular ER, absence of keratinization (k) ×15,000 and microfilaments (l) ×15,000 in RT + selenium supplemented patients