Journal of Cancer Research and Therapeutics Close
 

Figure 2: Influence of dietary restriction (DR) on microvessel density and apoptosis in the CT-2A brain tumor. DR was initiated 7 days before intracerebral tumor implantation and was continued for 11 days as we previously described. [37] H and E-stained tumor sections in an ad libitum (AL) -fed mouse (a) and in a DR mouse; (b) (100). Factor VIII imunostaining from the tumor grown in an AL mouse; (c) and in a DR mouse; (d) (200). TUNEL-positive apoptotic cells (arrows) from the tumor grown in an AL mouse; (e) and in a DR mouse; (f) (400). Each stained section was representative of the entire tumor. All images were produced from digital photography. The findings show that DR is antiangiogenic and proapoptotic (reprinted with permission from the British Journal of Cancer)[37]

Figure 2: Influence of dietary restriction (DR) on microvessel density and apoptosis in the CT-2A brain tumor. DR was initiated 7 days before intracerebral tumor implantation and was continued for 11 days as we previously described. [37] H and E-stained tumor sections in an ad libitum (AL) -fed mouse (a) and in a DR mouse; (b) (100). Factor VIII imunostaining from the tumor grown in an AL mouse; (c) and in a DR mouse; (d) (200). TUNEL-positive apoptotic cells (arrows) from the tumor grown in an AL mouse; (e) and in a DR mouse; (f) (400). Each stained section was representative of the entire tumor. All images were produced from digital photography. The findings show that DR is antiangiogenic and proapoptotic (reprinted with permission from the British Journal of Cancer)[37]