Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 16  |  Issue : 2  |  Page : 276--279

In vivo microscopy of arterial distribution embolic particles in rabbit mesenteric artery


Wei Li, Jun Yang, Chengtao Gu, Yu Yin, Zhi Li, Caifang Ni 
 Department of Vascular and Interventional Radiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

Correspondence Address:
Caifang Ni
Department of Vascular and Interventional Radiology, First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou 215006
China

Purpose: To study the arterial distribution of embosphere microsphere (EM) and polyvinyl alcohol (PVA) particles in rabbit mesenteric artery using in vivo microscopy.To study the arterial distribution of embosphere microsphere (EM) and polyvinyl alcohol (PVA) particles in rabbit mesenteric artery using in vivo microscopy. Methods: Sixteen New Zealand rabbits were divided into four groups, namely large PVA (560–710 μm), small PVA (150–350 μm), large EM (500–700 μm), and small EM (100–300 μm). The mesenteric arteries of the experimental animals were embolized under fluoroscopic guidance and visualized using in vivo microscopy. The embolized vessel diameter and arterial distribution of embolic agents were compared. Results: The diameters of occluded vessels in large PVA, small PVA, large EM, and small EM groups were 430.60 ± 67.30, 200.95 ± 70.54, 387.79 ± 92.51, and 143.81 ± 39.65 μm, respectively. PVA occluded significantly larger vessels than EM when the particle size was similar (P < 0.001). The proportion of EM at the bifurcation of the artery was significantly higher than that of PVA particles (large PVA < large EM, χ2 = 4.325, P < 0.038; small PVA < small EM, χ2 = 6.68, P < 0.01). Conclusion: Both PVA and EM could occlude vessels smaller than the particle size, and EM resulted in deeper penetration. The location of embolic particles in the artery is mainly related to the shape of particles.


How to cite this article:
Li W, Yang J, Gu C, Yin Y, Li Z, Ni C. In vivo microscopy of arterial distribution embolic particles in rabbit mesenteric artery.J Can Res Ther 2020;16:276-279


How to cite this URL:
Li W, Yang J, Gu C, Yin Y, Li Z, Ni C. In vivo microscopy of arterial distribution embolic particles in rabbit mesenteric artery. J Can Res Ther [serial online] 2020 [cited 2020 Aug 15 ];16:276-279
Available from: http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2020;volume=16;issue=2;spage=276;epage=279;aulast=Li;type=0