Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 10  |  Issue : 2  |  Page : 354--358

Malignant lymphoma in Eastern India: A retrospective analysis of 455 cases according to World Health Organisation classification


Santosh Kumar Mondal1, Palash Kumar Mandal1, Saptarshi Dutta Roy1, Subrata Chattopadhyay2, Shravasti Roy3, Pranab Kumar Biswas1 
1 Department of Pathology, Medical College, Kolkata, India
2 Department of Radiotherapy, Medical College, Kolkata, India
3 Department of Pathology, Thakurpukur Cancer Hospital, Kolkata, India

Correspondence Address:
Santosh Kumar Mondal
«DQ»Teenkanya Complex«DQ», Flat 1B, Block B, 204 R N Guha Road, Dumdum, Kolkata - 700028
India

Background: Malignant lymphoma (ML) is one of the most common cancers and is most prevalent in developed countries. The distribution of different subtypes of ML varies in the different geographical locations according to World Health Organization (WHO) classification. Aims and Objectives: The study was aimed to analyze different patterns of ML in Eastern India and to compare it with other geographical locations. Materials and Methods: Four hundred and fifty five patients of two large hospitals in Eastern India were included over a period of four years and were categorized according to WHO classification, using morphology and immunohistochemistry (IHC). Results: There were 347 (76.3%) non Hodgkin lymphomas (NHL), and 108 (23.7%) Hodgkin lymphomas (HL). Diffuse large B cell lymphoma (DLBCL) was the most common of the NHL type (35.2%) followed by the follicular lymphoma (19.3%). B cell lymphoblastic lymphoma was the least common type of NHL (1.4%). Mixed cellularity (33.3%) and nodular sclerosis (26.9%) were the two most common type of HL. Childhood lymphoma comprised of 12.5% of all ML. T cell NHL and HL were the common lymphomas in this age group. Conclusion: Incidence of follicular lymphoma is lower compared to western studies and mixed cellularity is most common subtype of HL unlike nodular sclerosis subtype in western world. Burkitt«SQ»s type NHL though is the most common subtype of childhood ML in many studies but in our study T cell NHL is the most common type of childhood ML.


How to cite this article:
Mondal SK, Mandal PK, Roy SD, Chattopadhyay S, Roy S, Biswas PK. Malignant lymphoma in Eastern India: A retrospective analysis of 455 cases according to World Health Organisation classification.J Can Res Ther 2014;10:354-358


How to cite this URL:
Mondal SK, Mandal PK, Roy SD, Chattopadhyay S, Roy S, Biswas PK. Malignant lymphoma in Eastern India: A retrospective analysis of 455 cases according to World Health Organisation classification. J Can Res Ther [serial online] 2014 [cited 2020 Aug 10 ];10:354-358
Available from: http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2014;volume=10;issue=2;spage=354;epage=358;aulast=Mondal;type=0