Journal of Cancer Research and Therapeutics

REVIEW ARTICLE
Year
: 2012  |  Volume : 8  |  Issue : 6  |  Page : 72--84

Toxicity with radiotherapy for oral cancers and its management: A practical approach


Trinanjan Basu, Sarbani G Laskar, Tejpal Gupta, Ashwini Budrukkar, Vedang Murthy, Jai P Agarwal 
 Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai - 400012, India

Correspondence Address:
Sarbani G Laskar
Department of Radiation Oncology, Room No. 128, Ground Floor, Main Building, Tata Memorial Hospital, Parel, Mumbai- 400 012
India

Radiotherapy-induced damage in the oral mucosa is the result of the deleterious effects of radiation, not only on the oral mucosa itself but also on the skin, adjacent salivary glands, bone, dentition, and masticatory apparatus. From basic skin care to dental and oral health maintenance, several ointments and lotions, oral and parenteral medications, biological response modifiers, cytoprotective drugs, newer radiation techniques and surgery have been introduced to combat and more importantly to prevent the development of these complications. Radiotherapy-induced oral complications involve complex and dynamic pathobiological processes. This in the immediate- and long-term course lowers the quality of life and predisposes patients to serious clinical disorders. Here, we focus on these oral complications of radiotherapy, highlight preventive and therapeutic developments, and review the current treatment options available for these disorders.


How to cite this article:
Basu T, Laskar SG, Gupta T, Budrukkar A, Murthy V, Agarwal JP. Toxicity with radiotherapy for oral cancers and its management: A practical approach.J Can Res Ther 2012;8:72-84


How to cite this URL:
Basu T, Laskar SG, Gupta T, Budrukkar A, Murthy V, Agarwal JP. Toxicity with radiotherapy for oral cancers and its management: A practical approach. J Can Res Ther [serial online] 2012 [cited 2020 Jan 25 ];8:72-84
Available from: http://www.cancerjournal.net/article.asp?issn=0973-1482;year=2012;volume=8;issue=6;spage=72;epage=84;aulast=Basu;type=0